| Date | Location | Result | |
| 5/15/2021 | Danville, Ky. | Centre 12, Denison 11 | |
| 5/8/2021 | Granville, Ohio | Denison 12, Kenyon 10 | |
| 5/4/2021 | Oberlin, OH | Oberlin 15, Allegheny 14 | |
| 5/2/2021 | Granville, Ohio | Denison 24, Wittenberg 4 | |
| May 01, 2021 | Wooster, Ohio | Wooster 21, Allegheny 9 | |
| May 01, 2021 | Oberlin, OH | Kenyon 16, Oberlin 5 | |
| 4/29/2021 | Meadville, Pa. | Wooster 15, Allegheny 11 | |
| 4/28/2021 | Springfield, OH | Denison 22, Wittenberg 4 | |
| 4/25/2021 | Meadville, Pa. | Kenyon 13, Allegheny 4 | |
| 4/24/2021 | Crawfordsville, IN | Wittenberg 23, Wabash 3 | |
| Apr 24, 2021 | Delaware, Ohio, USA | Ohio Wesleyan 19, Wooster 2 | |
| 4/22/2021 | Springfield, OH | Wittenberg 18, Wabash 4 | |
| Apr 21, 2021 | Gambier, OH | Kenyon 15, Allegheny 4 | |
| Apr 20, 2021 | Wooster, Ohio | Ohio Wesleyan 14, Wooster 10 | |
| Apr 17, 2021 | Wooster, Ohio | Kenyon 15, Wooster 7 | |
| 4/17/2021 | Springfield, OH | Wittenberg 12, DePauw 5 | |
| Apr 17, 2021 | Delaware, Ohio, USA | Ohio Wesleyan 22, Wabash 0 | |
| 4/17/2021 | Hiram, Ohio | Allegheny 23, Hiram 4 | |
| 4/14/2021 | Crawfordsville, IN | Ohio Wesleyan 32, Wabash 1 | |
| 4/14/2021 | Greencastle, Ind. | Wittenberg 10, DePauw 9 | |
| 4/14/2021 | Meadville, Pa. | Allegheny 20, Hiram 2 | |
| Apr 13, 2021 | Gambier, OH | Kenyon 15, Wooster 8 | |
| 4/13/2021 | Granville, Ohio | Denison 25, Walsh 6 | |
| 4/10/2021 | Crawfordsville, IN | Denison 32, Wabash 4 | |
| Apr 10, 2021 | Springfield, OH | Ohio Wesleyan 10, Wittenberg 4 | |
| 4/10/2021 | Fort Wayne, Ind. | Indiana Tech 11, DePauw 9 | |
| 4/10/2021 | Meadville, Pa. | Wooster 11, Allegheny 10 | |
| Apr 7, 2021 | Delaware, Ohio, USA | Ohio Wesleyan 16, Wittenberg 6 | |
| Apr 06, 2021 | Wooster, Ohio | Wooster 17, Allegheny 9 | |
| 4/6/2021 | Granville, OH | Denison 29, Wabash 2 | |
| Apr 03, 2021 | Wooster, Ohio | Wooster 26, Hiram 2 | |
| 4/3/2021 | Greencastle, Ind. | DePauw 28, Wabash 7 | |
| 4/3/2021 | Springfield, OH | Transylvania 14, Wittenberg 12 | |
| Apr 3, 2021 | Granville, Ohio | Denison 11, Ohio Wesleyan 10 | |
| 4/1/2021 | Crawfordsville, IN | DePauw 26, Wabash 6 | |
| Mar 31, 2021 | Delaware, Ohio, USA | Ohio Wesleyan 14, Denison 13 | |
| 3/31/2021 | Hiram, Ohio | Wooster 29, Hiram 1 | |
| 3/27/2021 | Springfield, OH | Wittenberg 13, Wooster 10 | |
| 3/27/2021 | Hiram, Ohio | Hiram 7, Mt. St. Joseph 4 | |
| 3/24/2021 | Crawfordsville, IN | Wabash 21, Anderson (IN) 7 | |
| 3/24/2021 | Granville, Ohio | Denison 26, Adrian 3 | |
| Mar 23, 2021 | Delaware, Ohio, USA | Ohio Wesleyan 17, Walsh 7 | |
| 3/21/2021 | Hanover, IN | Hanover 15, Wabash 5 | |
| 3/20/2021 | Springfield, OH | Kenyon 14, Wittenberg 12 | |
| 3/17/2021 | Hiram, Ohio | La Roche 10, Hiram 3 | |
| Mar 13, 2021 | Elmhurst, Ill. | ELMHURST 18, DePauw 8 | |
| 3/13/2021 | Danville, Ky. | Centre 14, Wittenberg 6 | |
| 3/12/2021 | Crawfordsville, IN | Wabash 13, Earlham 4 | |
| 3/10/2021 | Greencastle, Ind. | Transylvania 17, DePauw 7 | |
| 3/6/2021 | Greencastle, Ind. | DePauw 20, Earlham 2 | |
| 3/3/2021 | Anderson, Ind. | Wabash 11, Anderson (IN) 10 | |
| 2/27/2021 | Cincinnati, Ohio | Wabash 23, Mt. St. Joseph 8 | |
| Feb 27, 2021 | Bloomington, Ill. | Ill. Wesleyan 32, DePauw 7 |